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From Regulatory Networks to Microenvironments: Multiscale Multicellular Cancer Modeling and Simulation with CompuCell3D
Author/Presenter
Event Type
Workshop
Tags
Applications
Computational Science
Education and Training and Outreach
HPC Community Collaboration
HPC Training and Education
Machine Learning and Artificial Intelligence
Performance
Workforce
Registration Categories
W
TimeSunday, 14 November 20212pm - 2:15pm CST
Location223
DescriptionModeling the interplay of subcellular, intercellular and environmental factors is critical to producing meaningful, predictive simulations of cancer progression in vivo and testing biological hypotheses with virtual tissues. CompuCell3D is an open-source, cross-platform simulation environment that provides multiscale, multicellular biological modeling and simulation capabilities for a broad range of applications. New modeling, simulation and computing capabilities make CompuCell3D more relevant than ever to testing biological hypotheses in a multicellular context while considering processes that span scales from the subcellular to organismal scales. This talk presents new capabilities of CompuCell3D as relevant to modeling cancer onset and progression. The survey of new features includes capabilities like interactive Boolean network modeling, to computing leveraging high-performance computing environments. New features are demonstrated with examples related to proliferation, immune response and tissue recovery. An overview of an advanced application also demonstrates how CompuCell3D readily supports concurrent, collaborative development of complex modeling and simulation projects.
Author/Presenter
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